产品Product

肾脏疾病

Human Cystatin C (诊断原料,肾脏疾病)

Recombinant Human Cystatin C 


Catalog # DCI55        Derived From: Human Cells   


Description:

Recombinant human cystatin C/CST3 is produced by Mammalian expression system and the target gene encoding Ser27-Ala146 is expressed with a 6His tag at the C-terminus.

Accession:  P01034

Names(Known as):Cystatin-C;Cystatin-3;Gamma-trace;Neuroendocrine basic polypeptide;Post-gamma-globulin;CST3


Quality Control:

Mol Mass:  14.4kDa                    AP Mol Mass:  15-18kDa, reducing conditions

Purity:  Greater than 95% as determined by reducing SDS-PAGE.


Formulation:

Supplied as a 0.2 μm filtered solution of 10mM PB, 200mM NaCl, pH6.5.


Shipping:

The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.


Storage:

Reconstituted protein solution should be stored at ≤ -20°C.


Purification: 
Affinity purification chromatography.


Immunoreactivity: 
Confirmed by reaction with monoclonal antibodies specific to cystatin C.


Application:
Immunogen, calibrator or standard.


Background:

Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.


FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY



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