Recombinant Human Cystatin C
Catalog #: DCI55 Derived From: Human Cells
Recombinant human cystatin C/CST3 is produced by Mammalian expression system and the target gene encoding Ser27-Ala146 is expressed with a 6His tag at the C-terminus.
Names(Known as):Cystatin-C;Cystatin-3;Gamma-trace;Neuroendocrine basic polypeptide;Post-gamma-globulin;CST3
Mol Mass: 14.4kDa AP Mol Mass: 15-18kDa, reducing conditions
Purity: Greater than 95% as determined by reducing SDS-PAGE.
Supplied as a 0.2 μm filtered solution of 10mM PB, 200mM NaCl, pH6.5.
The product is shipped on dry ice pack. Upon receipt, store it immediately at the temperature listed below.
Reconstituted protein solution should be stored at ≤ -20°C.
Affinity purification chromatography.
Confirmed by reaction with monoclonal antibodies specific to cystatin C.
Immunogen, calibrator or standard.
Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B, H, K, L and S. As an inhibitor of cysteine proteinases, Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition), such as Alzheimer's disease.
FOR RESEARCH OR FURTHER MANUFACTURING USE ONLY