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Recombinant SARS-CoV-2 S-trimer Protein (BA.2.75, C-6His)(Cat. No.:DRA218)
DS
COA
价格:
规格:
50μg
500μg
1mg
数量:
-
1
+
分子量
136.9kDa
蛋白编号
P0DTC2
蛋白表达区间
Cys15-Gln1208
蛋白种属
SARS-CoV-2
表达系统
Human Cells
表观分子量
140-220kDa, reducing conditions
剂型描述
Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH7.4.
标签
C-6His
剂型
液体
生物活性-BLI
Loaded Human ACE-2-Fc(Cat#C05Y) on Protein A Biosensor, can bind SARS-CoV-2 S-trimer Protein-His(Cat#DRA218) with an affinity constant of 2.02 pM as determined in BLI assay. (Regularly tested)
Loaded Anti-2019-nCoV S1 mAb-Fc(Cat#NC025) on Protein A Biosensor, can bind SARS-CoV-2 S-trimer Protein-His(Cat#DRA218) with an affinity constant of 10.2 pM as determined in BLI assay. (Regularly tested)
产品描述
Recombinant SARS-CoV-2 S-trimer Protein is produced by our Mammalian expression system and the target gene encoding Cys15-Gln1208 is expressed with a 6His tag at the C-terminus. T19I, G142D, K147E, W152R, F157L, I210V, V213G, G257S, G339H, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, G446S, N460K, S477N, T478K, E484A, Q498R, N501Y, Y505H, D614G, H655Y, N679K, P681H, N764K, D796Y, Q954H and N969K mutations were identified in the SARS-CoV-2 variant (known as BA.2.75 lineage) which emerged in India. Six proline substitutions and furin cleavage site substitutions are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively.
保存条件
  • Reconstituted protein solution should be stored at ≤ -20°C.
  • Stable for at least 24 months when stored as instructed.
仅供科研或生产使用,不可直接应用于人体。
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